The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 13, 2018
Filed:
Sep. 12, 2014
Applicant:
Salk Institute for Biological Studies, La Jolla, CA (US);
Inventors:
Clodagh O'Shea, San Diego, CA (US);
Shigeki Miyake-Stoner, La Jolla, CA (US);
Colin Powers, San Diego, CA (US);
Assignee:
Salk Institute for Biological Studies, La Jolla, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/76 (2015.01); C12N 7/00 (2006.01); C12N 15/861 (2006.01); A61K 35/761 (2015.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
A61K 35/761 (2013.01); C12N 7/00 (2013.01); C12N 15/86 (2013.01); C07K 2319/20 (2013.01); C12N 2710/10034 (2013.01); C12N 2710/10052 (2013.01); C12N 2710/10345 (2013.01);
Abstract
Compositions and methods for retargeting adenovirus to a cell using chemical dimers are described. In particular, a recombinant adenovirus comprising a nucleic acid comprising a capsid-dimerizing agent binder conjugate and a ligand-dimerizing agent binder conjugate is provided.