The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 28, 2021
Filed:
Aug. 22, 2018
Applicant:
Salk Institute for Biological Studies, La Jolla, CA (US);
Inventors:
Clodagh O'Shea, San Diego, CA (US);
William Partlo, La Jolla, CA (US);
Colin Powers, San Diego, CA (US);
Assignee:
Salk Institute for Biological Studies, La Jolla, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/85 (2006.01); C07K 14/075 (2006.01); C12N 15/62 (2006.01); C07K 14/005 (2006.01); C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/85 (2013.01); C07K 14/005 (2013.01); C07K 14/075 (2013.01); C12N 7/00 (2013.01); C12N 15/62 (2013.01); C07K 2319/01 (2013.01); C07K 2319/60 (2013.01); C07K 2319/80 (2013.01); C12N 2015/859 (2013.01); C12N 2320/12 (2013.01); C12N 2320/52 (2013.01); C12N 2710/10331 (2013.01);
Abstract
Recombinant adenovirus genomes that include a heterologous open reading frame (ORF) and a self-cleaving peptide coding sequence are described. The recombinant adenovirus genomes and recombinant adenoviruses produced by the disclosed genomes can be used, for example, in high-throughput assays to measure virus replication kinetics. Methods for measuring replication kinetics of a recombinant adenovirus are also described.