The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 02, 2022
Filed:
Jun. 30, 2020
Applicant:
Salk Institute for Biological Studies, La Jolla, CA (US);
Inventors:
Clodagh O'Shea, San Diego, CA (US);
William Partlo, San Diego, CA (US);
Colin Powers, San Diego, CA (US);
Assignee:
Salk Institute for Biological Studies, La Jolla, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); C12N 2710/10011 (2013.01); C12N 2710/10043 (2013.01); C12N 2710/10051 (2013.01); C12N 2840/00 (2013.01);
Abstract
Recombinant adenovirus genomes that include an exogenous open reading frame (ORF) and a self-cleaving peptide coding sequence are described. Optimal placement of the exogenous genes for minimal impact on viral kinetics is further disclosed. Therapeutic applications of the recombinant adenoviruses are also described.