Location History:
- Tamil Nadu Chennai, IN (2022)
- Chennai, IN (2018 - 2023)
- Tamil Nadu, IN (2023)
Company Filing History:
Years Active: 2018-2023
Title: Aswini Thanigaivel: Innovator in Biologics and CRISPR Technology
Introduction
Aswini Thanigaivel is a prominent inventor based in Chennai, India. He has made significant contributions to the field of biotechnology, particularly in the development of innovative methods utilizing CRISPR technology. With a total of seven patents to his name, Thanigaivel is recognized for his groundbreaking work in protein engineering and therapeutic development.
Latest Patents
Thanigaivel's latest patents include a method for obtaining cells with modified fucosylation pathways. This method leads to the production of partially fucosylated and non-fucosylated protein products, specifically antibodies. The technology employs CRISPR to target the Fut8 and GMD genes, which are crucial for the production of these proteins. These innovations are essential for developing therapeutics and biomarkers, as well as for diagnosing and prognosing diseases.
Another notable patent involves vectors for cloning and expressing genetic material, including antibody genes. This patent describes methods for generating vectors that express antibody genes in various formats, such as Fab or scFv. The use of phage display technology allows for the cloning and screening of potential antibody genes, which are then transferred to yeast vectors for further screening. This approach offers numerous advantages, including efficient library preparation and identification of lead molecules against specific antigens.
Career Highlights
Aswini Thanigaivel is currently associated with Zumutor Biologics Inc., where he continues to push the boundaries of biotechnological research. His work has garnered attention for its potential applications in the medical field, particularly in the development of new therapies.
Collaborations
Thanigaivel collaborates with talented individuals such as Bhargav Prasad and Divya Unnikrishnan, who contribute to the innovative projects at Zumutor Biologics Inc. Their combined expertise enhances the research and development efforts within the company.
Conclusion
Aswini Thanigaivel stands out as a leading inventor in the field of biotechnology, with a focus on CRISPR technology and protein engineering. His contributions are paving the way for advancements in therapeutics and diagnostics, showcasing the impact of innovation in the life sciences.