The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 10, 2023
Filed:
Jul. 06, 2020
Zumutor Biologies Inc., San Francisco, CA (US);
Bhargav Prasad, Chennai, IN;
Divya Unnikrishnan, Bangalore, IN;
Jahnabi Hazarika, Bangalore, IN;
Kavitha Iyer Rodrigues, Bangalore, IN;
Maloy Ghosh, Bangalore, IN;
Pavithra M, Kundapur, IN;
Pravin Kumar D, Chennai, IN;
Sanghamitra Bhattacharjee, Bangalore, IN;
Sathyabalan M, Bangalore, IN;
Sankaranarayanan Srinivasan, Bangalore, IN;
Sohang Chatterjee, Bangalore, IN;
Sunit Maity, Bangalore, IN;
Veeresha K, Bangalore, IN;
Vivek Halan, Aravenu, IN;
Yogendra Manjunath B. M., Bangalore, IN;
Anuradha Hora, Sitapur, IN;
Bairavabalakumar N, Chennai, IN;
Karthika Nair, Bangalore, IN;
Aswini Thanigaivel, Chennai, IN;
Amol Maliwalave, Bangalore, IN;
Bharath R Shenoy, Bangalore, IN;
Rajeshwari Pendse, Bangalore, IN;
Prabhat Kumar Pathak, Varanas, IN;
Anisha Kurup, Delhi, IN;
Sahana Bhima Rao, Bangalore, IN;
Zumutor Biologics Inc., San Francisco, CA (US);
Abstract
The present disclosure relates to a method of obtaining a cell where fucosylation pathways are modified, leading to production of partially fucosylated and non-fucosylated protein products, specifically antibodies from the cell. The present disclosure employs the Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) technology. The method of the present disclosure targets the Fut8 gene and GMD gene in a cell. Such products are used in developing therapeutics and biomarkers, and in diagnosis and prognosis of diseases.