The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 12, 2022
Filed:
Dec. 21, 2015
Zumutor Biologics, Inc., Woburn, MA (US);
Sohang Chatterjee, Lexington, MA (US);
Kavitha Iyer Rodrigues, Bangalore, IN;
Maloy Ghosh, Bangalore, IN;
Sunit Maity, Bangalore, IN;
Divya Unnikrishnan, Bangalore, IN;
Yogendra Manjunath Bangalore Muniraju, Bangalore, IN;
Sathyabalan Murugesan, Bangalore, IN;
Pavithra Mukunda, Kundapur, IN;
Bhargav Prasad, Tamil Nadu Chennai, IN;
Veeresha Kamanagowda, Bangalore, IN;
Sanghamitra Bhattacharjee, Bangalore North Bangalore, IN;
Pravin Kumar Dakshinamurthy, Chennai, IN;
Vivek Halan, Tamil Nadu Aravenu, IN;
Sankaranarayanan Srinivasan, Bangalore, IN;
Anuradha Hora, Uttar Pradesh Sitapur, IN;
Bairavabalakumar Natarajan, Tamil Nadu Chennai, IN;
Karthika Nair, Karnataka Bangalore, IN;
Aswini Thanigaivel, Tamil Nadu Chennai, IN;
Amol Maliwalave, Karnataka Bangalore, IN;
Bharath Ravindra Shenoy, Bangalore, IN;
Sahana Bhima Rao, Karnataka Bangalore, IN;
Subhra Prakash Chakrabarty, Karnataka Bangalore, IN;
Ashvini Kumar Dubey, Vidyaranyapura Bangalore, IN;
Amir Khan, Uttar Pradesh Aligarh, IN;
Anurag Tiwari, Lamni Badalalpur Varanasi, IN;
Santosh Kumar, Jharkhand Charki Giridih, IN;
Shivani Patel, Madhya Pradesh Adhartal, IN;
Nikitha M, Karnataka Bangalore, IN;
ZUMUTOR BIOLOGICS INC., Woburn, MA (US);
Abstract
The present disclosure relates to a method of generating an antibody library, not limiting to a human naïve antibody gene expression library encompassing a pool of nucleic acid sequences derived from a natural antibody repertoire comprising humoral immunity from healthy and genetically diverse human populations. More specifically, the method employs a combination of phage and/or yeast antibody surface display concept which allows to screen large antibody library size and facilitates better folding of antibody structure. The present disclosure also relates to a human naïve antibody library generated by employing the process of the present disclosure, a set of primers employed in the method and application(s) of said antibody library.