The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 10, 2023
Filed:
Apr. 06, 2017
Zumutor Biologics, Inc., Woburn, MA (US);
Sohang Chatterjee, Lexington, MA (US);
Kavitha Iyer Rodrigues, Bangalore, IN;
Maloy Ghosh, Bangalore, IN;
Sunit Maity, Bangalore, IN;
Divya Unnikrishnan, Bangalore, IN;
Yogendra Manjunath Bangalore Muniraju, Bangalore, IN;
Sathyabalan Murugesan, Bangalore, IN;
Pavithra Mukunda, Kundapur, IN;
Bhargav Prasad, Tamil Nadu, IN;
Veeresha Kamanagowda, Bangalore, IN;
Sanghamitra Bhattacharjee, Doorvaninagar Bangalore North Bangalore, IN;
Pravin Kumar Dakshinamurthy, Tamil Nadu, IN;
Vivek Halan, Tamil Nadu, IN;
Sankaranarayanan Srinivasan, Bangalore, IN;
Anuradha Hora, Uttar Pradesh, IN;
Bairavabalakumar Natarajan, Tamil Nadu, IN;
Karthika Nair, Karnataka, IN;
Aswini Thanigaivel, Tamil Nadu, IN;
Amol Maliwalave, Karnataka, IN;
Bharath Ravindra Shenoy, Karnataka, IN;
Sahana Bhima Rao, Karnataka, IN;
Subhra Prakash Chakrabarty, Karnataka, IN;
Ashvini Kumar Dubey, Bangalore, IN;
Amir Khan, Aligarh, IN;
Ankurina Sharma, Bangalore, IN;
Rashmi Sharma, Uttarakhand, IN;
Anurag Tiwari, Benares, IN;
Santosh Kumar, Jharkhand, IN;
Shivani Patel, Adhartal Madhya Pradesh, IN;
Nikitha M, Karnataka, IN;
ZUMUTOR BIOLOGICS, INC., Woburn, MA (US);
Abstract
The present disclosure relates to vectors for cloning and expressing genetic material including but not limiting to antibody gene or parts thereof and methods of generating said vectors. Said vectors express the antibody genes in different formats such as Fab or scFv as a part of intertransfer system, intratransfer system or direct cloning and expression in individual display systems. In particular, phage display technology is used to clone and screen potential antibody genes in phagemid which is followed by the transfer of said genes to yeast vector for further screening and identification of lead molecules against antigens. The present vectors have numerous advantages including uniquely designed inserts/expression cassettes resulting in efficient and smooth transfer of clonal population from phage to yeast vectors resulting in efficient library preparation and identification of lead molecules.