Location History:
- Monmouth Junction, NJ (US) (2006)
- Niskayuna, NY (US) (2012 - 2018)
- Belle Mead, NJ (US) (2011 - 2020)
- Hillsborough, NJ (US) (2022)
Company Filing History:
4 out of 51,920 
3 out of 135 
1 out of 31 
Years Active: 2006-2022
Title: Anuradha Sekher: Innovator in Nucleic Acid Amplification Technologies
Introduction
Anuradha Sekher is a prominent inventor based in Belle Mead, NJ (US). She has made significant contributions to the field of nucleic acid amplification, holding a total of 8 patents. Her innovative work has advanced methodologies that are crucial for various applications in biotechnology and molecular biology.
Latest Patents
Among her latest patents is the "Endonuclease-assisted isothermal amplification using contamination-free reagents." This patent discloses methods and kits for conducting endonuclease-assisted DNA amplification reactions using decontaminated primer solutions that have been pre-treated with a nuclease. The invention also includes nucleic acid amplification assays that utilize nuclease-resistant, inosine-containing primers and endonuclease V enzymes to introduce a nick into target DNA, ultimately generating amplicons of the desired DNA.
Another notable patent is the "Ligation-based RNA amplification." This patent describes methods for the amplification, purification, and detection of nucleic acid sequences, particularly RNA. One aspect of this method involves the hybridization and subsequent ligation of a nucleic acid structure to the nucleic acid sequence intended for manipulation. The methods require that the nucleic acid structure consists of both a double-stranded region and a single-stranded region, with the single-stranded region being complementary to the RNA sequence of interest.
Career Highlights
Anuradha has worked with esteemed organizations such as General Electric Company and GE Healthcare Bio-Sciences Corporation. Her experience in these companies has allowed her to develop and refine her innovative techniques in nucleic acid amplification.
Collaborations
Throughout her career, Anuradha has collaborated with notable professionals, including John Richard Nelson and Robert Scott Duthie. These collaborations have contributed to her success and the advancement of her research.
Conclusion
Anuradha Sekher is a trailblazer in the field of nucleic acid amplification technologies. Her patents and contributions continue to influence the biotechnology landscape, showcasing her dedication to innovation and research.