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For the Inventor, By the Inventor

Durham, NC, United States of America

Inspire Pharmaceuticals, Inc.

USPTO Granted Patents = 91

% Expired Patents = 44.0



Forward Citations = 1,287

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68 inventors (with patents filed for the assignee):

goldMedal Benjamin R Yerxa (49 out of 54 patents)

silverMedal Janet L Rideout (31 out of 63 patents)

bronzeMedal William Pendergast (28 out of 48 patents)

4.  Sammy Ray Shaver (22 out of 31 patents)

5.  Ward M Peterson (20 out of 21 patents)

6.  James G Douglass, Iii (19 out of 19 patents)

7.  Karla M Jacobus (18 out of 20 patents)

8.  José L Boyer (17 out of 19 patents)

9.  Paul Steven Watson (15 out of 23 patents)

10.  Robert Plourde, Jr (10 out of 13 patents)

11.  Edward G Brown (10 out of 12 patents)

12.  John W Lampe (9 out of 19 patents)

13.  Christopher S Crean (9 out of 9 patents)

14.  David J Drutz (9 out of 12 patents)

15.  David J Slade (7 out of 9 patents)


Core Competencies:
Rho Kinase
Purinergic Receptor Agonists
Platelet Aggregation
Cytoskeletal Compounds
Dry Eye Disease
Dinucleoside Polyphosphates
Neuropathic Diseases
Pulmonary Diseases
Cystic Fibrosis
Glaucoma Treatments
Vaginal Secretions

91 patents:

1. 8604218 - Cytoskeletal active rho kinase inhibitor compounds, composition and use (2013-12-10),
2. 8604205 - Cytoskeletal active rho kinase inhibitor compounds, composition and use (2013-12-10),
3. 8410147 - Method for treating diseases associated with alterations in cellular integrity using Rho kinase inhibitor compounds (2013-04-02),
4. 8349806 - Method of treating blepharitis (2013-01-08),
5. 8299096 - Method for treating pulmonary diseases using rho kinase inhibitor compounds (2012-10-30),
6. 8207195 - Method for treating neurological and neuropathic diseases using rho kinase inhibitor compounds (2012-06-26),
7. 8168597 - Method for treating cystic fibrosis (2012-05-01),
8. 8158796 - Process for the preparation of Rho-kinase inhibitor compounds (2012-04-17),
9. 8158776 - [object Object] (2012-04-17),
10. 8097600 - Method of increasing tear production with purinergic receptor agonists (2012-01-17),
11. 8071779 - Cytoskeletal active rho kinase inhibitor compounds, composition and use (2011-12-06),
12. 8039465 - Cytoskeletal active compounds, composition and use (2011-10-18),
13. 8008274 - P1-(2'-deoxycytidine 5′-)P4-(uridine 5′-)tetraphosphate, tetra-(alkali metal) salt, for treating sinusitis (2011-08-30),
14. D640554 - Medicine dispenser (2011-06-28),
15. 7947850 - Process for the preparation of 3,4-disubstituted-thiazolidin-2-ones (2011-05-24),
Company Overview
Inspire Pharmaceuticals, Inc., based in Durham, NC, specializes in the development of innovative therapies focusing on Rho kinase inhibitors. The company is engaged in advancing treatments for various conditions, including dry eye disease and neuropathic disorders. Its research encompasses a range of core technology topics such as purinergic receptor agonists and cytoskeletal compounds, aiming to address significant unmet medical needs in pulmonary and other diseases. Inspire's commitment to scientific excellence drives its exploration of novel therapeutic pathways.
Profile summary synthesized from public USPTO records and patent filings.

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USPTO Data Jan 1 1976 - Oct 20 2026

91 Patents

#13 in Durham, NC

#103 in North Carolina

#4,109 in US

#8,453 in the World

Durham, NC (US)
Durham, NC, United States of America

Inspire Pharmaceuticals, Inc.

Forward Citations = 1,287

68 inventors:

goldMedal Benjamin R Yerxa (49 out of 54 patents)

silverMedal Janet L Rideout (31 out of 63 patents)

bronzeMedal William Pendergast (28 out of 48 patents)

4.  Sammy Ray Shaver (22 out of 31 patents)

5.  Ward M Peterson (20 out of 21 patents)

IDiyas Innovation Intelligence. (2026). Company Patent Portfolio: Inspire Pharmaceuticals, Inc.. Retrieved from https://idiyas.com/company/inspire-pharmaceuticals

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Data Sources: USPTO Patent Grant XML, Patent Center, EPO & CIPO • Normalized by IDiyas Innovation Graph. Methodology & provenance architecturePlease report any incorrect information to [email protected]
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