The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 26, 2012

Filed:

Jun. 26, 2009
Applicants:

Tomas Navratil, Carrboro, NC (US);

John W. Lampe, Cary, NC (US);

Emilee H. Fulcher, Cary, NC (US);

Ward M. Peterson, Morrisville, NC (US);

Inventors:

Tomas Navratil, Carrboro, NC (US);

John W. Lampe, Cary, NC (US);

Emilee H. Fulcher, Cary, NC (US);

Ward M. Peterson, Morrisville, NC (US);

Assignee:

Inspire Pharmaceuticals, Inc., Whitehouse Station, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/47 (2006.01); A61K 31/415 (2006.01); A61K 31/40 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention is directed to methods of preventing or treating neurological or neuropathic diseases or conditions associated with excessive inflammation, neurodegeneration, neuro-remodeling, and axonal/neurite retraction. Particularly, this invention relates to methods treating neurological or neuropathic diseases such as cerebral ischemia, stroke, neuropathic pain, spinal cord injury, Alzheimer's disease, and multiple sclerosis, using novel rho kinase inhibitor compounds. The method comprises identifying a subject in need of the treatment, and administering to the subject an effective amount of a novel rho kinase inhibitor compound to treat the disease.


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