Cary, NC, United States of America

Edward G Brown

USPTO Granted Patents = 12 

Average Co-Inventor Count = 3.2

ph-index = 6

Forward Citations = 195(Granted Patents)


Location History:

  • Lake Oswego, OR (US) (1996)
  • Apex, NC (US) (2004)
  • Cary, NC (US) (2005 - 2011)

Company Filing History:


Years Active: 1996-2011

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12 patents (USPTO):Explore Patents

Title: Innovations by Edward G. Brown: A Patented Legacy in Pharmaceutical Sciences

Introduction

Edward G. Brown, an inventive mind hailing from Cary, NC, holds an impressive portfolio of 12 patents. His work primarily focuses on developing pharmaceutical compounds that provide stability and efficacy for various medical applications.

Latest Patents

Brown's most recent innovations include significant advancements in nucleotide chemistry. One of his patents details P,P-di(uridine 5'-)tetraphosphate and its tetra-alkali metal salts, such as tetrasodium and tetrapotassium. This invention emphasizes the water-soluble and nontoxic nature of the compounds, which are easier to handle during production. Notably, these tetra-monovalent alkali metal salts exhibit greater resilience to hydrolysis than their mono-, di-, or tri-acid counterparts, enhancing their stability and shelf life. His methods for synthesizing these compounds notably reduce the production time to three days or less.

In another groundbreaking patent, Brown introduces degradation-resistant mononucleoside phosphate compounds. These innovative compounds provide pharmaceutical benefits similar to those of dinucleotides. By modifying a mononucleotide with a degradation-resistant substituent on its terminal phosphate, the resulting compounds offer improved stability and therapeutic potential for treating epithelial tissue diseases and disorders related to platelet aggregation.

Career Highlights

Throughout his career, Edward G. Brown has contributed significantly to the pharmaceutical industry. He has been associated with Inspire Pharmaceuticals, Inc., where he collaborated with teams aiming to advance medical science through innovation.

Collaborations

Brown has worked alongside noteworthy professionals in the field, including Benjamin R. Yerxa and Ward M. Peterson. These collaborations have enriched his research and contributed to the successful patenting of innovative compounds that address pressing health concerns.

Conclusion

Edward G. Brown's extensive patent portfolio and innovative spirit have left a notable mark in the pharmaceutical sector. His focus on stability and efficiency in drug development exemplifies the tremendous potential of his inventions, paving the way for advancements in treatments for various medical conditions.

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