The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 14, 2008
Filed:
Nov. 21, 2005
James G. Douglass, Iii, Apex, NC (US);
Benjamin R. Yerxa, Raleigh, NC (US);
Sammy R. Shaver, Chapel Hill, NC (US);
Ward M. Peterson, Morrisville, NC (US);
Edward G. Brown, Cary, NC (US);
Christopher S. Crean, Pittsboro, NC (US);
José L. Boyer, Chapel Hill, NC (US);
James G. Douglass, III, Apex, NC (US);
Benjamin R. Yerxa, Raleigh, NC (US);
Sammy R. Shaver, Chapel Hill, NC (US);
Ward M. Peterson, Morrisville, NC (US);
Edward G. Brown, Cary, NC (US);
Christopher S. Crean, Pittsboro, NC (US);
José L. Boyer, Chapel Hill, NC (US);
Inspire Pharmaceutical, Inc., Durham, NC (US);
Abstract
The present invention relates to mononucleoside phosphate compounds that have the benefits of a dinucleotide pharmaceutical. These mononucleoside phosphates can be made from a mononucleotide that has been modified by attaching a degradation-resistant substituent on the terminal phosphate of a polyphosphate mononucleotide. By attaching this degradation-resistant substituent, the stability from degradation matches or exceeds those of certain dinucleotides. The mononucleoside phosphate compounds of the present invention are useful in preventing and treating epithelial tissue diseases or diseases or disorders associated with platelet aggregation.