The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 03, 2006
Filed:
Feb. 27, 2002
Benjamin R. Yerxa, Raleigh, NC (US);
James G. Douglass, Iii, Apex, NC (US);
Sammy Ray Shaver, Chapel Hill, NC (US);
Ward M. Peterson, Morrisville, NC (US);
Edward G. Brown, Cary, NC (US);
Christopher S. Crean, Cary, NC (US);
Benjamin R. Yerxa, Raleigh, NC (US);
James G. Douglass, III, Apex, NC (US);
Sammy Ray Shaver, Chapel Hill, NC (US);
Ward M. Peterson, Morrisville, NC (US);
Edward G. Brown, Cary, NC (US);
Christopher S. Crean, Cary, NC (US);
Inspire Pharmaceuticals, Inc., Durham, NC (US);
Abstract
The present invention relates to mononucleoside phosphate compounds that have the benefits of a dinucleotide pharmaceutical. These mononucleoside phosphates can be made from a mononucleotide that has been modified by attaching a degradation resistant substituent on the terminal phosphate of a polyphosphate mononucleotide. By attaching this degradation resistant substituent, the stability from degradation matches or exceeds those of certain dinucleotides.