The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 01, 2006
Filed:
Jan. 15, 2003
Benjamin R. Yerxa, Raleigh, NC (US);
Robert Plourde, Jr., Chapel Hill, NC (US);
Edward G. Brown, Cary, NC (US);
Ward M. Peterson, Morrisville, NC (US);
Benjamin R. Yerxa, Raleigh, NC (US);
Robert Plourde, Jr., Chapel Hill, NC (US);
Edward G. Brown, Cary, NC (US);
Ward M. Peterson, Morrisville, NC (US);
Inspire Pharmaceuticals, Inc., Durham, NC (US);
Abstract
The present invention is directed to a method of reducing intraocular pressure. The method comprises administering to a subject a pharmaceutical composition comprising an effective amount of a purinerginic receptor ligand, which is a mononucleoside polyphosphate or dinucleoside polyphosphate defined by general Formula I. The method of the present invention is useful in the treatment or prevention of ocular hypertension, such as glaucoma, including primary and secondary glaucoma. The method can be used alone to reduce intraocular pressure. The method can also be used in conjunction with other therapeutic agents or adjunctive therapy commonly used to treat glaucoma to enhance the therapeutic effect of reducing the intraocular pressure.