The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 27, 2015
Filed:
May. 14, 2013
China National Research Institute of Food and Fermentation Industries, Beijing, CN;
Muyi Cai, Beijing, CN;
Ruizeng Gu, Beijing, CN;
Weixue Yi, Beijing, CN;
Jun Lu, Beijing, CN;
Yong Ma, Beijing, CN;
Zhe Dong, Beijing, CN;
Yaguang Xu, Beijing, CN;
Xingchang Pan, Beijing, CN;
Yongqing Ma, Beijing, CN;
Feng Lin, Beijing, CN;
Zhentao Jin, Beijing, CN;
Liang Chen, Beijing, CN;
Lu Lu, Beijing, CN;
Wenying Liu, Beijing, CN;
Abstract
The present invention discloses a method for producing antihypertensive active peptides with corn germ protein as the material. The method comprises an alkali-heat treatment and continuous enzymolysis of the corn germ protein. The components with molecular weight less than 1000 Da in the active peptides obtained according to the present method account for more than 92%, and alanine-tyrosine (Ala-Tyr, AY) as the characteristic peptide fragments in the antihypertensive peptides accounts for more than 0.6%, so that the active peptides have a good ACE inhibitory activity in vitro as well as stability against temperature, pH and major gastrointestinal digestive enzymes, and have a significant effect of lowering blood pressure on spontaneous hypertension rats in vivo. The active peptides can be applied as a new functional nutrient to development and production of food, health food and pharmaceutical.