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For the Inventor, By the Inventor

Wuxi, China

Zhiming Rao

This inventor holds 16 USPTO granted patents and 2 published patent applications. Top assignee: Jiangnan University. Active years: 2018-2025.

USPTO Granted Patents = 16 

% Patents Active = 87.5

Average Co-Inventor Count = 6.2

ph-index = 1

Forward Citations = 4(Granted Patents)


Location History:

  • Wuxi, CN (2018 - 2021)
  • Jiangsu, CN (2020 - 2021)

Company Filing History:

goldMedal16 out of 558 
 
Jiangnan University
 patents

Years Active: 2018-2025

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16 patents (USPTO):Explore Patents
1. 12486498 - L-ARGININE-GLYCINE AMIDINOTRANSFERASE AND USE THEREOF IN THE PRODUCTION OF GUANIDINOACETIC ACID (2025-12-02),
2. 12480112 - GLUTAMATE DECARBOXYLASE MUTANT WITH IMPROVED PH TOLERANCE AND USE THEREOF IN SYNTHESIS OF GAMMA-AMINOBUTYRIC ACID (2025-11-25),
3. 12473528 - ESCHERICHIA COLI FOR SYNTHESIZING L-VALINE, CONSTRUCTION METHOD AND USE THEREOF (2025-11-18),
4. 11203742 - Sucrose phosphorylase mutant with improved enzyme activity and construction method thereof and use thereof (2021-12-21),
5. 11098287 - 17β-hydroxysteroid dehydrogenase mutants and application thereof (2021-08-24),
6. 11060076 - Method for producing 1,2-amino alcohol compound by whole cell transformation (2021-07-13),
7. 11001871 - Method for producing 9alpha-hydroxy androstane-4-alkene-3,17-diketone by enzymatic conversion (2021-05-11),
8. 11001825 - Thermophilic L-asparaginase mutant and screening and fermentation methods thereof (2021-05-11),
9. 10865404 - Aspartase mutant, recombinant expression vector and recombinant bacterium containing aspartase mutant, and use thereof (2020-12-15),
10. 10851352 - Mycobacterium neoaurum-derived steroid C27-monooxygenase and application thereof (2020-12-01),
11. 10731138 - Formate dehydrogenase mutant with improved enzyme activity and stability and construction method thereof (2020-08-04),
12. 10612054 - Single-cell factory for efficiently synthesizing α-aminobutyric acid and construction and application thereof (2020-04-07),
13. 10465218 - Method for increasing yield of L-arginine by knocking out Flavin reductases (2019-11-05),
14. 10351816 - Signal peptide, L-glutamic acid synthesized using konjac flour and methods of using same (2019-07-16),
15. 10329592 - Signal peptide, L-glutamic acid synthesized using konjac flour and methods of using same (2019-06-25),

Title: Zhiming Rao: Innovator in Genetic Engineering

Introduction

Zhiming Rao is a prominent inventor based in Wuxi, China. He has made significant contributions to the field of genetic engineering, holding a total of 16 patents. His work focuses on enhancing enzyme activities, which has implications for industrial applications.

Latest Patents

One of his latest patents is titled "Sucrose phosphorylase mutant with improved enzyme activity and construction method thereof and use thereof." This invention relates to a sucrose phosphorylase mutant that has been engineered to exhibit improved enzyme activity. The mutant is derived from sucrose phosphorylase and has undergone site-directed mutagenesis. This advancement allows for the efficient production of 2-O-α-D-glycerol glucoside in a 5 L fermentation tank, paving the way for its large-scale industrial application.

Another notable patent is "17β-hydroxysteroid dehydrogenase mutants and application thereof." This patent discloses several mutants of 17β-hydroxysteroid dehydrogenase, including V107A, T155N, H164Y, and V107A/T155N/H164Y. These mutants demonstrate significantly higher specific enzyme activities compared to the wild-type enzyme, with activities reaching up to 5.15 U/mg. This enhancement is crucial for various biological applications.

Career Highlights

Zhiming Rao is affiliated with Jiangnan University, where he continues to advance research in genetic engineering. His innovative work has positioned him as a key figure in the development of enzyme technology.

Collaborations

He collaborates with notable colleagues, including Meijuan Xu and Xian Zhang, who contribute to his research endeavors.

Conclusion

Zhiming Rao's contributions to genetic engineering through his patents and research at Jiangnan University highlight his role as an influential inventor in the field. His work not only enhances our understanding of enzyme activity but also opens new avenues for industrial applications.

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