Location History:
- Osaka, JP (2013 - 2015)
- Tokyo, JP (2023)
Company Filing History:
4 out of 107 
3 out of 415 
1 out of 3 Years Active: 2013-2023
Title: Yuzuru Kitahara: Innovator in Mammalian Cell Expression Vectors
Introduction
Yuzuru Kitahara is a prominent inventor based in Osaka, Japan. He has made significant contributions to the field of biotechnology, particularly in the development of mammalian cell expression vectors. With a total of 4 patents, his work has advanced the ability to produce high levels of foreign gene-derived proteins.
Latest Patents
Among his latest patents, Kitahara has developed a vector that includes a translation-impaired dihydrofolate reductase gene cassette and a ubiquitously acting chromatin opening element. This invention provides mammalian cell expression vectors that enable host cells to produce high levels of proteins derived from foreign genes. The introduction of a ubiquitously acting chromatin opening element into an expression vector allows for the selection of strains that can grow in hypoxanthine-thymidine-free medium, resulting in increased protein production. Another notable patent involves the construction of expression vectors that facilitate high-level production of foreign gene-derived proteins in mammalian host cells. This includes a translation-impaired dihydrofolate reductase gene cistron and a gene cassette designed for the incorporation of foreign genes.
Career Highlights
Throughout his career, Kitahara has worked with notable organizations such as Fuso Pharmaceutical Industries, Ltd. and Hokkaido University. His experience in these institutions has contributed to his expertise in the field of biotechnology and patent development.
Collaborations
Kitahara has collaborated with esteemed colleagues, including Keiichi Yamamoto and Yasuhiko Suzuki. These partnerships have further enriched his research and innovations in the biotechnology sector.
Conclusion
Yuzuru Kitahara's contributions to the field of biotechnology through his innovative patents and collaborations have significantly impacted the production of proteins in mammalian cells. His work continues to influence advancements in genetic engineering and biotechnology.
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