Xiaoyun Lu

Title: Innovations of Xiaoyun Lu

Introduction

Xiaoyun Lu is a prominent inventor based in Guangdong, China. She has made significant contributions to the field of biochemistry and pharmacology, holding a total of four patents. Her work focuses on developing compounds and enzymes that have important applications in medicine and biotechnology.

Latest Patents

One of her latest patents involves Alkynylphenylbenzamide compounds and their applications. This patent describes compounds that can act as protein kinase inhibitors, effectively inhibiting the activity of TRK protein kinase and the proliferation, migration, and invasion of various tumor cells. These compounds are characterized by good pharmacokinetics and low toxicity, making them promising candidates for therapeutic use.

Another notable patent pertains to an enzyme that synthesizes hydroxyl acetaldehyde and/or 1,3-dihydroxyacetone by catalyzing formaldehyde. This invention includes a site-directed mutation of benzoylformate decarboxylase (BFD), creating a mutant enzyme capable of polymerizing formaldehyde. The process generates acetyl phosphoric acid from hydroxyl acetaldehyde or 1,3-dihydroxyacetone, providing a pathway from formaldehyde to acetyl coenzyme A in three steps.

Career Highlights

Xiaoyun Lu has worked with esteemed institutions such as the Chinese Academy of Sciences and Guangzhou Eggbio Co., Ltd. Her research has significantly advanced the understanding of enzyme functions and their applications in drug development.

Collaborations

She has collaborated with notable colleagues, including Ke Ding and Zhengchao Tu, contributing to various research projects and innovations in her field.

Conclusion

Xiaoyun Lu's innovative work in developing new compounds and enzymes showcases her dedication to advancing science and medicine. Her contributions are paving the way for future breakthroughs in therapeutic applications.