The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 05, 2023

Filed:

Sep. 20, 2022
Applicant:

Shenzhen Newdel Biotech Co., Ltd., Guangdong, CN;

Inventors:

Xiaoyun Lu, Guangdong, CN;

Zhang Zhang, Guangdong, CN;

Ke Ding, Guangdong, CN;

Shuang Xiang, Guangdong, CN;

Jie Wang, Guangdong, CN;

Zhengchao Tu, Guangdong, CN;

Zhimin Zhang, Guangdong, CN;

Xia Tang, Guangdong, CN;

Zuqin Wang, Guangdong, CN;

Xun He, Guangdong, CN;

Feng Jin, Guangdong, CN;

Shuihua Zhang, Guangdong, CN;

Zhenwei Li, Guangdong, CN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); C07D 487/04 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 9/0053 (2013.01); A61P 35/00 (2018.01);
Abstract

The present disclosure relates to Alkynylphenylbenzamide compounds and the applications thereof. The said Alkynylphenylbenzamide compounds have the structure shown in Formula (I). The compounds can be used as protein kinase inhibitors, which can effectively inhibit the activity of TRK protein kinase and the proliferation, migration and invasion of various tumor cells. At the same time, it has the characteristics of good pharmacokinetics and low toxicity.


Find Patent Forward Citations

Loading…