Hubei, China

Xiaodan Guo



Average Co-Inventor Count = 9.0

ph-index = 1


Company Filing History:


Years Active: 2025

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2 patents (USPTO):Explore Patents

Title: Innovations by Inventor Xiaodan Guo

Introduction

Xiaodan Guo is a notable inventor based in Hubei, China. She has made significant contributions to the field of pharmaceutical development, particularly in the area of receptor antagonists. With a total of two patents to her name, her work focuses on compounds that have promising applications in treating various diseases.

Latest Patents

Xiaodan Guo's latest patents include a lysophosphatidic acid receptor antagonist and a preparation method for it. These compounds exhibit high LPAR1 antagonist activity and selectivity, along with low toxicity and good metabolic stability. They show potential for preventing or treating LPAR1-related diseases. The IC50 values of some of these compounds can be as low as 300 nM or even below 50 nM. Additionally, the CC50 value range of these compounds can be as high as 200 μM or above, indicating their safety profile. Furthermore, these compounds demonstrate good metabolic stability in humans, mice, and rats.

Another significant patent by Guo involves triazole compounds and their preparation method. These triazole compounds also exhibit good LPAR1 antagonistic activity and selectivity, low toxicity, and good metabolic stability. They can be utilized for preventing or treating LPAR1-related diseases or disorders. The IC50 values of some triazole compounds can be below 300 nM, even reaching 50 nM. The CC values of these compounds can exceed 200 μM, showcasing their potential for therapeutic use.

Career Highlights

Xiaodan Guo is currently employed at Wuhan Ll Science and Technology Development Co., Ltd. Her work at this company has allowed her to focus on innovative research and development in the pharmaceutical sector.

Collaborations

Some of her notable coworkers include Jun Lou and Yongkai Chen, who contribute to her research endeavors.

Conclusion

Xiaodan Guo's innovative work in developing receptor antagonists highlights her significant role in advancing pharmaceutical research. Her contributions have the potential to lead to new treatments for various diseases, showcasing the importance of her inventions in the medical field.

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