The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 28, 2026
Filed:
Dec. 29, 2020
Applicant:
Wuhan Ll Science and Technology Development Co., Ltd., Wuhan, CN;
Inventors:
Jun Lou, Wuhan, CN;
Yongkai Chen, Wuhan, CN;
Yihan Zhang, Wuhan, CN;
Xiaodan Guo, Wuhan, CN;
Lina Qian, Wuhan, CN;
Li Liu, Wuhan, CN;
Wei Peng, Wuhan, CN;
Fei Rong, Wuhan, CN;
Chaodong Wang, Wuhan, CN;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 217/26 (2006.01); C07D 237/28 (2006.01); C07D 239/72 (2006.01); C07D 401/04 (2006.01); C07D 401/12 (2006.01);
U.S. Cl.
CPC ...
C07D 217/26 (2013.01); C07D 237/28 (2013.01); C07D 239/72 (2013.01); C07D 401/04 (2013.01); C07D 401/12 (2013.01);
Abstract
Disclosed is a fused ring compound and an application thereof. Disclosed is a fused ring compound represented by formula I, a pharmaceutically acceptable salt, a stereoisomer, a tautomer, an isotope compound, a crystal form, a nitrogen oxide, a solvate, or a solvate of the pharmaceutically acceptable salt thereof. The fused ring compound of the present invention has high P2X4 antagonistic activity, excellent selectivity, low toxicity and excellent metabolic stability.