Vladimir M Subbotin

Title: Innovations of Vladimir M Subbotin

Introduction

Vladimir M Subbotin is a notable inventor based in Madison, WI (US). He has made significant contributions to the field of molecular biology, particularly in the area of nucleic acid delivery systems. With a total of 3 patents, his work has the potential to impact various medical applications.

Latest Patents

One of his latest patents is titled "Process for mixing nucleic acids with transfection reagents for delivery." This patent describes a method for transfecting nucleic acids into cells in vivo by mixing transfection reagents and nucleic acids immediately before injection. The process involves introducing the transfection reagents and nucleic acids into a mixing chamber through separate portals, mixing them to form particles, and then pushing these particles into a mammal within one second of introduction, thereby facilitating cell transfection. Another significant patent is "Delivery of molecules and complexes to mammalian cells in vivo." This patent discloses a system for delivering molecules or complexes to extravascular mammalian cells via an intravascular administration route. The method involves inserting an injection solution into mammalian vasculature at an appropriate rate, which transiently increases the volume of extravascular fluid in the tissue, thus enhancing the delivery of the molecule to the target cell.

Career Highlights

Vladimir M Subbotin has worked with prominent companies such as Roche Madison Inc. and Mirus Bio Corporation. His experience in these organizations has contributed to his expertise in the field of biotechnology and molecular delivery systems.

Collaborations

Throughout his career, Subbotin has collaborated with notable individuals, including Jon Asher Wolff and Vladimir G Budker. These collaborations have likely enriched his research and development efforts.

Conclusion

Vladimir M Subbotin's innovative work in nucleic acid delivery systems showcases his significant contributions to biotechnology. His patents reflect a commitment to advancing medical science and improving therapeutic delivery methods.