The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 15, 2009

Filed:

Jul. 28, 2003
Applicants:

Jon A. Wolff, Madison, WI (US);

Vladimir G. Budker, Middleton, WI (US);

Hans Herweijer, Madison, WI (US);

James E. Hagstrom, Middleton, WI (US);

Sean D. Monahan, Madison, WI (US);

Julia Hegge, Monona, WI (US);

Vladimir Subbotin, Madison, WI (US);

Inventors:

Jon A. Wolff, Madison, WI (US);

Vladimir G. Budker, Middleton, WI (US);

Hans Herweijer, Madison, WI (US);

James E. Hagstrom, Middleton, WI (US);

Sean D. Monahan, Madison, WI (US);

Julia Hegge, Monona, WI (US);

Vladimir Subbotin, Madison, WI (US);

Assignee:

Roche Madison Inc., Madison, WI (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 38/08 (2006.01); C07K 14/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed is a system for providing in vivo delivery of molecules or complexes to extravascular mammalian cells using an intravascular administration route. The molecules or complexes are inserted in an injection solution into a mammalian vasculature. Insertion of the injection solution at an appropriate rate transiently increases the volume of extravascular fluid in the tissue thereby facilitating delivery of the molecule to the cell.


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