The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 05, 2020
Filed:
Jul. 27, 2017
Applicant:
Vladimir M Subbotin, Madison, WI (US);
Inventor:
Vladimir M Subbotin, Madison, WI (US);
Assignee:
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/87 (2006.01); A61K 31/7105 (2006.01); A61K 48/00 (2006.01); C12N 15/88 (2006.01); C12N 15/11 (2006.01);
U.S. Cl.
CPC ...
C12N 15/87 (2013.01); A61K 31/7105 (2013.01); A61K 48/0008 (2013.01); C12N 15/88 (2013.01); C12N 15/111 (2013.01); C12N 2310/14 (2013.01); C12N 2310/3517 (2013.01); C12N 2320/32 (2013.01);
Abstract
A process is described for transfecting nucleic acids into cells in vivo by mixing transfection reagents and the nucleic acids immediately prior to injection. The process comprises introducing the transfection reagents and the nucleic acids into a mixing chamber by a first portal for introducing the transfection reagents, a second portal for introducing the nucleic acids where the transfection reagents and nucleic acids are mixed together to form particles and pushing the particles through an injection portal into a mammal in less than 1 second after introduction thereby transfecting cells in the mammal.