Location History:
- State College, PA (US) (2003)
- Chicago, IL (US) (2007)
- Columbia, MO (US) (2009 - 2020)
Company Filing History:
5 out of 873 
3 out of 1,303 
2 out of 4,131 
Years Active: 2003-2020
Title: Innovations of Timothy E. Glass
Introduction
Timothy E. Glass is a notable inventor based in State College, PA (US), recognized for his contributions to the field of molecular imaging and chemical sensing. With a total of nine patents to his name, he has made significant advancements in the development of novel fluorophores and sensing compounds.
Latest Patents
One of his latest patents is titled "Rhodol fluorophores for near-infrared imaging." This invention encompasses a novel near-infrared-emitting molecular fluorophore and probes that are advantageous for both in vitro and in vivo research studies. The fluorophore is robust, photostable, and designed for easy bioorthogonal conjugation, making it biocompatible and capable of emitting at 711 nm in aqueous conditions. These fluorophores can be utilized to fluorescently tag biological molecules or structures of interest, serving as optical reporters for specific biomarkers or analytes. Their ability to switch from 'off' to 'on' makes them particularly useful for cellular assays and preclinical small animal imaging, with potential applications in clinical settings.
Another significant patent is the "Fluorescent chemical sensor for biological amines." This invention provides a variety of fluorescence sensing compounds characterized by a coumarin-3-aldehyde scaffold with a pendant aryl moiety. It includes a method for detecting primary amines in biological samples, particularly for the selective labeling and imaging of catecholamines in live and fixed secretory cells.
Career Highlights
Timothy E. Glass has worked with esteemed institutions such as the University of Missouri and the Penn State Research Foundation. His work has significantly impacted the fields of molecular imaging and chemical sensing, showcasing his innovative approach to scientific challenges.
Collaborations
Throughout his career, Timothy has collaborated with notable individuals, including Kenneth Hettie and Ronald Thaddeus Raines. These collaborations have contributed to the advancement of his research and the successful development of his patented technologies.
Conclusion
Timothy E. Glass is a distinguished inventor whose work in molecular imaging and chemical sensing has led to significant innovations. His contributions continue to influence research and applications in various scientific fields.