The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 11, 2011
Filed:
Apr. 21, 2009
Ronald T. Raines, Madison, WI (US);
Sunil S. Chandran, Fremont, CA (US);
Timothy E. Glass, Columbia, MO (US);
Luke D. Lavis, Madison, WI (US);
Ronald T. Raines, Madison, WI (US);
Sunil S. Chandran, Fremont, CA (US);
Timothy E. Glass, Columbia, MO (US);
Luke D. Lavis, Madison, WI (US);
Wisconsin Alumni Research Foundation, Madison, WI (US);
The Penn State Research Foundation, Univeristy Park, PA (US);
Abstract
Latent fluorescent compounds, comprising a fluorescent molecule with one or more blocking groups attached and optionally one or more urea-containing groups are provided. The urea-containing group can be used to further attach one or more molecules of interest, such as proteins, peptides or nucleic acids. The blocking group(s) is released from the latent fluorescent compound by reaction with a trigger, forming the fluorescent molecule which can be detected. Also provided herein are methods of using latent fluorescent compounds to detect triggers.