The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 25, 2019
Filed:
Mar. 21, 2014
Applicant:
The Curators of the University of Missouri, Columbia, MO (US);
Inventors:
Timothy Glass, Columbia, MO (US);
Kevin Gillis, Columbia, MO (US);
Kenneth Hettie, Columbia, MO (US);
Assignee:
The Curators of the University of Missouri, Columbia, MO (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 403/04 (2006.01); G01N 33/52 (2006.01); C09K 11/06 (2006.01); C07D 311/16 (2006.01); C07D 409/04 (2006.01);
U.S. Cl.
CPC ...
G01N 33/52 (2013.01); C07D 311/16 (2013.01); C07D 409/04 (2013.01); C09K 11/06 (2013.01); C09K 2211/1088 (2013.01);
Abstract
The invention is provides for a variety of fluorescence sensing compounds characterized generally as having a coumarin-3-aldehyde scaffold with a pendant aryl moiety at the C4-position of the scaffold. The further provides a method for detecting primary amines in a biological sample using said compounds. Especially, for the selective labeling and imaging of catecholamines in live and fixed secretory cells.