Kenneth Hettie

Title: Kenneth Hettie: Innovator in Near-Infrared Imaging and Fluorescent Sensing

Introduction

Kenneth Hettie is a notable inventor based in Columbia, MO (US), recognized for his contributions to the field of molecular fluorophores and fluorescent sensing compounds. With a total of 4 patents, Hettie's work focuses on advancing imaging techniques and detection methods in biological research.

Latest Patents

Hettie's latest patents include innovative technologies such as "Rhodol fluorophores for near-infrared imaging." This patent encompasses a novel near-infrared-emitting molecular fluorophore that is robust, photostable, and biocompatible. The fluorophore emits at 711 nm in aqueous conditions and is designed for use in both in vitro and in vivo research studies. It can fluorescently tag biological molecules or structures and serves as an optical reporter for specific biomarkers, making it highly valuable for cellular assays and preclinical small animal imaging.

Another significant patent is the "Fluorescent chemical sensor for biological amines." This invention features fluorescence sensing compounds characterized by a coumarin-3-aldehyde scaffold. It provides a method for detecting primary amines in biological samples, particularly for the selective labeling and imaging of catecholamines in live and fixed secretory cells.

Career Highlights

Hettie has had a distinguished career, contributing to research at prominent institutions such as the University of Missouri and Stanford University. His work has significantly impacted the fields of biochemistry and molecular imaging, showcasing his dedication to advancing scientific knowledge.

Collaborations

Throughout his career, Hettie has collaborated with esteemed colleagues, including Timothy E Glass and Jessica L Klockow. These partnerships have fostered innovation and have been instrumental in the development of his patented technologies.

Conclusion

Kenneth Hettie's contributions to the fields of near-infrared imaging and fluorescent sensing highlight his role as a leading inventor. His innovative patents and collaborations continue to influence research methodologies in biological sciences.