Location History:
- Alameda, CA (US) (2005 - 2013)
- Lexington, MA (US) (2013 - 2023)
- Richmond, CA (US) (2014 - 2023)
Company Filing History:
8 out of 160 
5 out of 71 
3 out of 145 
Years Active: 2005-2025
Title: **Siyuan Tan: Innovator in Gene Therapy**
Introduction
Siyuan Tan, based in Lexington, MA, is a prominent innovator with a remarkable portfolio of 19 patents to his name. His groundbreaking work primarily focuses on gene therapy, particularly related to the treatment of bleeding disorders such as hemophilia. This article delves into his latest patents, career highlights, and collaborations that showcase his contributions to biomedical advancements.
Latest Patents
Among Siyuan Tan's noteworthy innovations are his recent patents concerning optimized Factor IX and Factor VIII genes. The patent for the optimized Factor IX gene presents codon-optimized sequences, vectors, and host cells that facilitate the production of polypeptides encoded by these sequences. Additionally, it proposes methods for treating bleeding disorders by administering a codon-optimized Factor IX nucleic acid sequence or the corresponding polypeptide. Similarly, his patent for the optimized Factor VIII gene follows a like focus, outlining codon-optimized sequences and methods aimed at combatting hemophilia through innovative genetic approaches.
Career Highlights
Siyuan Tan has made significant strides in his career by working with notable companies in the biotechnology sector. His tenure at Sangamo Biosciences, Inc. and Bioverativ Therapeutics Inc. has allowed him to contribute to cutting-edge research and development processes in gene therapy. Tan’s expertise and innovative mindset have been crucial in driving forward projects that address critical health challenges.
Collaborations
Throughout his career, Siyuan Tan has collaborated with esteemed colleagues in the field, including Fyodor Urnov and Philip D. Gregory. Together, they have fostered an environment of creativity and research excellence, which has undoubtedly influenced many of the successful developments in their respective projects.
Conclusion
Siyuan Tan stands out as a leading inventor in the realm of gene therapy, particularly in the treatment of hemophilia. His extensive patent portfolio underscores his commitment to innovation, and his collaborative efforts with industry experts further enhance the impact of his work. As gene therapy continues to evolve, Tan's contributions pave the way for groundbreaking therapies that hold the potential to save lives and improve patient outcomes.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.