The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 2025
Filed:
Sep. 30, 2020
Applicant:
Bioverativ Therapeutics Inc., Waltham, MA (US);
Inventors:
Siyuan Tan, Lexington, MA (US);
Robert T. Peters, Needham, MA (US);
Tongyao Liu, Lexington, MA (US);
Assignee:
BIOVERATIV THERAPEUTICS INC., Waltham, MA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 9/64 (2005.12);
U.S. Cl.
CPC ...
C12N 9/644 (2012.12); C12Y 304/21022 (2012.12); C07K 2319/31 (2012.12); C12N 2800/22 (2012.12);
Abstract
The present invention provides codon optimized Factor IX sequences, vectors and host cells comprising codon optimized Factor IX sequences, polypeptides encoded by codon optimized Factor IX sequences, and methods of producing such polypeptides. The present invention also provides methods of treating bleeding disorders such as hemophilia comprising administering to the subject a codon optimized Factor IX nucleic acid sequence or the polypeptide encoded thereby.