The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 19, 2013

Filed:

May. 17, 2011
Applicants:

Philip D. Gregory, Orinda, CA (US);

Jeffrey C. Miller, San Leandro, CA (US);

David Paschon, Oakland, CA (US);

Edward J. Rebar, San Francisco, CA (US);

Siyuan Tan, Lexington, MA (US);

Fyodor Urnov, Richmond, CA (US);

Lei Zhang, Davis, CA (US);

Inventors:

Philip D. Gregory, Orinda, CA (US);

Jeffrey C. Miller, San Leandro, CA (US);

David Paschon, Oakland, CA (US);

Edward J. Rebar, San Francisco, CA (US);

Siyuan Tan, Lexington, MA (US);

Fyodor Urnov, Richmond, CA (US);

Lei Zhang, Davis, CA (US);

Assignee:

Sangamo BioSciences, Inc., Richmond, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C12Q 1/37 (2006.01); C12P 19/34 (2006.01); C07K 7/23 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed herein are polypeptides, polynucleotides encoding, cells and organisms comprising novel DNA-binding domains, including TALE DNA-binding domains. Also disclosed are methods of using these novel DNA-binding domains for modulation of gene expression and/or genomic editing of endogenous cellular sequences.


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