The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 09, 2019
Filed:
Sep. 20, 2017
Applicant:
Sangamo Therapeutics, Inc., Richmond, CA (US);
Inventors:
Philip D. Gregory, Richmond, CA (US);
Jeffrey C. Miller, Richmond, CA (US);
David Paschon, Richmond, CA (US);
Edward J. Rebar, Richmond, CA (US);
Siyuan Tan, Richmond, CA (US);
Fyodor Urnov, Richmond, CA (US);
Lei Zhang, Richmond, CA (US);
Assignee:
Sangamo Therapeutics, Inc., Richmond, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/22 (2006.01); C12N 15/52 (2006.01); C12N 15/90 (2006.01); C12N 15/62 (2006.01); C12N 15/85 (2006.01); C07K 14/195 (2006.01); C12N 15/82 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/907 (2013.01); C07K 14/195 (2013.01); C12N 9/22 (2013.01); C12N 15/52 (2013.01); C12N 15/62 (2013.01); C12N 15/8213 (2013.01); C12N 15/85 (2013.01); C12Y 301/21004 (2013.01); A61K 38/00 (2013.01); C07K 2319/80 (2013.01);
Abstract
Disclosed herein are polypeptides, polynucleotides encoding, cells and organisms comprising novel DNA-binding domains, including TALE DNA-binding domains. Also disclosed are methods of using these novel DNA-binding domains for modulation of gene expression and/or genomic editing of endogenous cellular sequences.