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For the Inventor, By the Inventor

Cambridge, MA, United States of America

Robert H Hesse

USPTO Granted Patents = 25

Average Co-Inventor Count = 2.1

ph-index = 9

Forward Citations = 145(Granted Patents)


Location History:

  • Cambridge, MA (US) (1976 - 1995)
  • Winchester, MA (US) (1996 - 2007)

Company Filing History:

goldMedal22 out of 24 
 
Research Institute for Medicine & Chemistry, Inc.
 patents
silverMedal3 out of 832,812 
Other
 patents

Years Active: 1976-2007

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25 patents (USPTO):Explore Patents
1. 7235552 - Cholenic acid amides and pharmaceutical compositions thereof (2007-06-26),
2. 6967195 - 2-substituted pregna-1-3,5(10) triene and chola-1,3,5(10) triene derivatives and their biological activity (2005-11-22),
3. 6881730 - Steroid compounds with a c17-alkyl side chain and an aromatic a-ring for use in therapy (2005-04-19),
4. 6372926 - 17-side chain alkynyl-and 20-oxopregna-derivatives of vitamin D, methods for their production and pharmaceutical compositions thereof (2002-04-16),
5. 6013814 - Vitamin D analogues (2000-01-11),
6. 5872140 - Vitamin D analogues (1999-02-16),
7. 5811562 - Vitamin-D amide derivatives (1998-09-22),
8. 5786347 - Vitamin D amine and amide derivatives (1998-07-28),
9. 5756733 - Vitamin D amide derivatives (1998-05-26),
10. 5686435 - Vitamin D amide derivatives (1997-11-11),
11. 5494905 - Vitamin D amide derivatives (1996-02-27),
12. 5472957 - Chemical compounds and process (1995-12-05),
13. 4772433 - Vitamin D analogues (1988-09-20),
14. 4670190 - 1-.alpha.-hydroxy vitamin D compounds and process for preparing same (1987-06-02),
15. 4554105 - Process for the preparation of 1-hydroxylated vitamin D compounds (1985-11-19),

Title: The Innovative Contributions of Robert H. Hesse

Introduction: Robert H. Hesse, based in Cambridge, MA, is a prolific inventor with an impressive portfolio of 25 patents. His work primarily focuses on the development of novel pharmaceutical compounds and biological activities that have significant implications in the field of medicine.

Latest Patents: Among his latest contributions are groundbreaking patents such as the "Cholenic acid amides and pharmaceutical compositions thereof." This patent introduces novel sterol derivatives that play a crucial role in modulating cell growth and differentiation. The active compounds derived from these inventions have shown a promising therapeutic ratio, characterized by their low levels of calcaemic activity. Another notable patent is on "2-substituted pregna-1-3,5(10) triene and chola-1,3,5(10) triene derivatives and their biological activity." These compounds exhibit potent cell modulating activity, highlighting their antiproliferative and antiangiogenic effects.

Career Highlights: Robert H. Hesse has made significant strides in his career, contributing to advancing pharmaceutical sciences through his innovative inventions. His affiliation with the Research Institute for Medicine & Chemistry, Inc. has been instrumental in his research endeavors, where he has focused on creating and enhancing therapeutic compounds.

Collaborations: Throughout his career, Hesse has collaborated with esteemed professionals in his field, including Derek H. Barton and Sundara Katugam Setty. These collaborations have enhanced the scope and impact of his research, leading to esteemed patents that contribute to the scientific community.

Conclusion: Robert H. Hesse's dedication to innovation and invention within the pharmaceutical industry is exemplified through his substantial patent portfolio and impactful collaborations. His work continues to resonate in the realms of medicine and chemistry, showcasing the critical role inventors play in advancing health solutions and therapies for broader applications.

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