The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 19, 2005
Filed:
May. 11, 2003
Robert Henry Hesse, Winchester, MA (US);
Sundara Katugam Srinivasasetty Setty, Cambridge, MA (US);
Malathi Ramgopal, Andover, MA (US);
Sanga Kugabalnsooriar, Burlington, MA (US);
Robert Henry Hesse, Winchester, MA (US);
Sundara Katugam Srinivasasetty Setty, Cambridge, MA (US);
Malathi Ramgopal, Andover, MA (US);
Sanga Kugabalnsooriar, Burlington, MA (US);
Research Institute for Medicine & Chemistry, Inc., Cambridge, MA (US);
Abstract
Compounds of Formula (I) in which: Rand R, which may be the same or different, each represents a lower alkyl, alkenyl or alkynyl group; Rrepresents a methyl group having α- or β-configuration; Rrepresents a hydrogen atom or an etherifying or esterifying group; Rrepresents a hydrogen atom, a hydroxyl group or a lower alkoxy group; X represents a group OR, wherein Ris as defined above, or a group NRRwherein Rrepresents a hydrogen atom, an aliphatic or araliphatic organic group, or an acyl group comprising an aliphatic, araliphatic or aryl organic group linked to the nitrogen atom by way of a carbonyl group; and Ris a hydrogen atom or a lower alkyl group; Y represents a lower alkylene, alkenylene or alkynylene group optionally substituted by a hydroxyl, etherified hydroxyl or esterified hydroxyl group; and the dotted lines signify that double bonds may be present at the 16(17)-position and/or either at the 6(7)- and 8(9)-positions or at the 7(8)-position exhibit potent effects on modulation of cell growth and differentiation, while having low calcaemic activity.