This inventor holds 10 USPTO granted patents and 2 published patent applications, plus 2 CIPO patents and 3 EPO patents. Top assignees: Harvard College, Taiho Pharmaceutical Company Limited. Active years: 1997-2019.
Location History:
- Newton, MA (US) (2015 - 2017)
- Brookline, MA (US) (1997 - 2019)
Company Filing History:


Years Active: 1997-2019
Title: Innovations of Randall W. King
Introduction
Randall W. King is a notable inventor based in Brookline, MA (US). He has made significant contributions to the field of proteasome activity enhancement, holding a total of 10 patents. His work focuses on addressing proteinopathies, which are conditions resulting from the inefficiency of the proteasome in eliminating harmful proteins.
Latest Patents
Among his latest patents are two key inventions. The first is titled "Compositions and methods for enhancing proteasome activity." This invention addresses the inefficiency of the proteasome in eliminating harmful proteins and preventing the formation of pathogenic aggregates. It describes how the inhibition of the proteasome-associated deubiquitinase Usp14 can lead to increased proteasome efficiency. The second patent, "Tricyclic proteasome activity enhancing compounds," also focuses on the inhibition of Usp14 to enhance proteasome activity and treat proteinopathies.
Career Highlights
Throughout his career, Randall W. King has worked with prestigious institutions, including Harvard College and Taiho Pharmaceutical Company Limited. His research has significantly advanced the understanding of proteasome function and its implications for various diseases.
Collaborations
Some of his notable coworkers include Daniel J. Finley and Byung-Hoon Lee. Their collaborative efforts have contributed to the development of innovative solutions in the field of proteasome research.
Conclusion
Randall W. King is a distinguished inventor whose work in enhancing proteasome activity has the potential to impact the treatment of proteinopathies significantly. His contributions to science and innovation continue to pave the way for future advancements in this critical area of research.