The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 08, 2015
Filed:
Mar. 08, 2010
Applicants:
Randall King, Newton, MA (US);
Xing Zeng, Jamaica Plain, MA (US);
Shantanu Gaur, Canonsburg, PA (US);
Inventors:
Randall King, Newton, MA (US);
Xing Zeng, Jamaica Plain, MA (US);
Shantanu Gaur, Canonsburg, PA (US);
Assignee:
President and Fellows of Harvard College, Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/155 (2006.01); A61K 31/18 (2006.01); A61K 31/198 (2006.01);
U.S. Cl.
CPC ...
A61K 31/198 (2013.01); A61K 31/155 (2013.01); A61K 31/18 (2013.01);
Abstract
The invention provides an anti-proliferative composition comprising a non-peptide analog of the C-terminal isoleucine-arginine (IR) tail motif of an activator of an anaphase promoting complex (APC). The invention further provides methods of inhibiting the ubiquitination activity of the APC by administering compositions of the invention.