The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 24, 2015

Filed:

Jun. 17, 2011
Applicants:

Eun Sun Park, Arlington, MA (US);

Henry E. Pelish, Newton, MA (US);

Astrid S. Clarke, Andover, MA (US);

Grace L. Williams, Waltham, MA (US);

Maria Paola Castaldi, Brookline, MA (US);

Alexander Arefolov, Newton, MA (US);

Jennifer E. Ring, Lowell, MA (US);

Matthew D. Shair, Lexington, MA (US);

Randall W. King, Newton, MA (US);

Inventors:

Eun Sun Park, Arlington, MA (US);

Henry E. Pelish, Newton, MA (US);

Astrid S. Clarke, Andover, MA (US);

Grace L. Williams, Waltham, MA (US);

Maria Paola Castaldi, Brookline, MA (US);

Alexander Arefolov, Newton, MA (US);

Jennifer E. Ring, Lowell, MA (US);

Matthew D. Shair, Lexington, MA (US);

Randall W. King, Newton, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/48 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/485 (2013.01); G01N 2500/02 (2013.01);
Abstract

The present invention provides methods of identifying an agent that modulates PRPK, TPRKB, OSGEP, LAGE3 and its homologs, PRPK/TPRKB complex, and/or KEOPS complex. The present invention also provides compositions of such agents and methods of treating a disease, disorder, or condition associated with PRPK, TPRKB, OSGEP, LAGE3 and its homologs family (CT antigens), PRPK/TPRKB complex, and/or KEOPS complex using such an agent or composition.


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