Location History:
- Somesville, ME (US) (2009)
- Mount Desert, ME (US) (2012 - 2023)
Company Filing History:
11 out of 90 
1 out of 1,552 
Years Active: 2009-2024
Title: The Innovative Contributions of Michael V Wiles
Introduction
Michael V Wiles is a prominent inventor based in Mount Desert, ME (US), known for his significant contributions to the field of biomedical research. With a total of 11 patents to his name, Wiles has made remarkable advancements in the development of humanized mouse models, which are crucial for therapeutic protein research.
Latest Patents
Among his latest patents, Wiles has developed improved humanized IgG1 FcRn mouse models. These models are designed to estimate the serum half-life of therapeutic proteins, such as monoclonal antibodies. Another notable patent involves genetically modified NSG mice that lack functional major histocompatibility complex I and II. This innovation allows for the administration of human immune cells and tumor cells to these immunodeficient mice, facilitating various assays for test substances.
Career Highlights
Wiles has had a distinguished career, working with reputable organizations such as The Jackson Laboratory and the University of Massachusetts. His work has significantly impacted the field of immunology and therapeutic development, showcasing his expertise and dedication to advancing scientific knowledge.
Collaborations
Throughout his career, Wiles has collaborated with esteemed colleagues, including Robert A Taft and G Charles Ostermeier. These partnerships have further enriched his research and contributed to the success of his innovative projects.
Conclusion
Michael V Wiles stands out as a leading inventor in the biomedical field, with a strong portfolio of patents that reflect his commitment to innovation. His work continues to influence the development of therapeutic models, paving the way for future advancements in medicine.