The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 03, 2024

Filed:

Feb. 25, 2022
Applicant:

The Jackson Laboratory, Bar Harbor, ME (US);

Inventors:

Michael V. Wiles, Bar Harbor, ME (US);

Derry C. Roopenian, Bar Harbor, ME (US);

Greg Christianson, Bar Harbor, ME (US);

Benjamin E. Low, Bar Harbor, ME (US);

Assignee:

The Jackson Laboratory, Bar Harbor, ME (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01K 67/027 (2024.01); A01K 67/0278 (2024.01); C07K 14/735 (2006.01); C07K 16/00 (2006.01); C07K 16/28 (2006.01); C07K 16/46 (2006.01);
U.S. Cl.
CPC ...
A01K 67/0278 (2013.01); C07K 14/70535 (2013.01); C07K 16/283 (2013.01); A01K 2207/15 (2013.01); A01K 2227/105 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/52 (2013.01); C07K 2317/72 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01);
Abstract

The present disclosure provides improved humanized IgG1 FCRN mouse models for use, for example, in estimating serum half-life of therapeutic proteins such as monoclonal antibodies.


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