Location History:
- DK 1923 Frederiksberg, DK (1996 - 1998)
- DK 1923 Fredriksberg, DK (2001)
- 2000 Fredericksberg, DK (2002)
- Fredriksberg, DK (1997 - 2004)
- Frederiksburg, DK (2004)
- Wayland, MA (US) (2000 - 2006)
- Lexington, MA (US) (1998 - 2007)
- 2000 Frederiksberg, DK (2002 - 2008)
- Madison, CT (US) (2011)
- Woodbridge, CT (US) (2002 - 2016)
Company Filing History:
5 out of 496 
4 out of 1,035 
3 out of 62 
Years Active: 1996-2016
Title: The Innovative Contributions of Michael Egholm
Introduction: Michael Egholm, based in Lexington, MA, is a prominent figure in the field of molecular biology, holding an impressive portfolio of 42 patents. His groundbreaking work has significantly advanced the development of methods for nucleic acid amplification, among other innovations, thus cementing his role as a key contributor to the scientific community.
Latest Patents: Among Egholm’s latest patents is a method for nucleic acid amplification that focuses on replicating complex nucleic acid samples, such as genomic samples. This method effectively employs one or a few primers, leading to the efficient amplification of highly complex nucleic acid samples. The unique aspect of this invention lies in the capacity to displace replicated strands from nucleic acid molecules in the sample, improving the overall amplification process.
Another recent patent involves binary probe and clamp compositions for target hybridization detection. This innovative method utilizes probes that serve as substrates for exonuclease cleavage, allowing for the quantitation and detection of PCR products through real-time and endpoint measurements. The versatility of this invention is highlighted by probes and clamps that can be labeled with various fluorescent dyes and other moieties, providing enhanced labeling and detection capabilities.
Career Highlights: Throughout his career, Egholm has worked with several esteemed organizations, including Applera Corporation, contributing his expertise in the development of novel biochemical methods and technologies. His extensive experience in the field has positioned him as a leading innovator in nucleic acid research.
Collaborations: Egholm has collaborated with notable figures such as Peter Eigil Nielsen and Rolf Henrik Berg. These partnerships have fostered significant advancements in the field, leveraging their collective expertise to push the boundaries of nucleic acid technology further.
Conclusion: Michael Egholm’s contributions to the field of molecular biology through his numerous patents showcase his innovative spirit and dedication to advancing scientific research. His work continues to influence future developments in nucleic acid amplification and detection methods, solidifying his legacy as an impactful inventor in the life sciences.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.