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Branford, CT, United States of America

454 Life Sciences Corporation

USPTO Granted Patents = 31

% Expired Patents = 54.8

CIPO Patents = 6

EPO Patents = 10

Trademarks = 1

Forward Citations = 5,639

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52 inventors (with patents filed for the assignee):

Jonathan Marc Rothberg (12 out of 403 patents)

Yi-Ju Chen (11 out of 12 patents)

John Harris Leamon (11 out of 44 patents)

4. Jan Berka (10 out of 12 patents)

5. Michael Weiner (9 out of 40 patents)

6. Kenton L Lohman (8 out of 10 patents)

7. Keith McDade (7 out of 7 patents)

8. John W Simpson (7 out of 30 patents)

9. Gary James Sarkis (6 out of 8 patents)

10. Vinod B Makhijani (5 out of 9 patents)

11. Maithreyan Srinivasan (5 out of 10 patents)

12. Steve Lefkowitz (4 out of 4 patents)

13. Joel S Bader (4 out of 9 patents)

14. Scott B Dewell (4 out of 4 patents)

15. Christopher M Colangelo (4 out of 4 patents)

Core Competencies:

Nucleic Acid Amplification

Nucleotide Flow Orders

HIV Tropism Detection

Bead Emulsion

DNA Sequencing

Microwell Arrays

Emulsion Breaking

Error Correction

Recursive Algorithm

In Vitro Sorting

Amplifying Methods

Thin Film Coating

31 patents: Sort by Forward Citations

1. 10240192 - Bead emulsion nucleic acid amplification (2019-03-26),

2. 10192024 - System and method for generation and use of optimal nucleotide flow orders (2019-01-29),

3. 9808806 - System and method for automated nucleic acid amplification (2017-11-07),

4. 9624519 - System and method for nucleic acid amplification (2017-04-18),

5. 9587274 - System and method for correcting primer extension errors in nucleic acid sequence data (2017-03-07),

6. RE46293 - System and method for detection of HIV tropism variants (2017-01-30),

7. 9317654 - System and method to correct out of phase errors in DNA sequencing data by use of a recursive algorithm (2016-04-19),

8. 9057693 - Silicon oxide nanopore wetting and stabilization by molecular coating (2015-06-16),

9. 8790876 - Methods of amplifying and sequencing nucleic acids (2014-07-29),

10. 8765380 - Bead emulsion nucleic acid amplification (2014-07-01),

11. 8748102 - Bead emulsion nucleic acid amplification (2014-06-10),

12. 8609339 - System and method for emulsion breaking and recovery of biological elements (2013-12-17),

13. 8364417 - System and method to correct out of phase errors in DNA sequencing data by use of a recursive algorithm (2013-01-29),

14. 8344123 - System and method for detection of HIV tropism variants (2013-01-01),

15. 8301394 - System and method for correcting primer extension errors in nucleic acid sequence data (2012-10-30),

Company Overview

454 Life Sciences Corporation, based in Branford, Connecticut, specializes in advanced sequencing technologies that enhance genomic research and applications. The company is known for its innovative approaches in next-generation sequencing, which facilitate the analysis of complex biological systems. By providing tools and solutions for researchers, 454 Life Sciences plays a crucial role in the fields of genomics, personalized medicine, and biotechnology, contributing to advancements in healthcare and scientific understanding.

Profile summary synthesized from public USPTO records and patent filings.

Company Badge

USPTO Data Jan 1 1976 - Oct 13 2026

31 Patents

#7 in Branford, CT

#282 in Connecticut

#10,927 in US

#21,260 in the World

Branford, CT, United States of America

454 Life Sciences Corporation

Forward Citations = 5,639

52 inventors:

Jonathan Marc Rothberg (12 out of 403 patents)

Yi-Ju Chen (11 out of 12 patents)

John Harris Leamon (11 out of 44 patents)

4. Jan Berka (10 out of 12 patents)

5. Michael Weiner (9 out of 40 patents)

IDiyas Innovation Intelligence. (2026). Company Patent Portfolio: 454 Life Sciences Corporation. Retrieved from https://idiyas.com/company/454-life-sciences

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Data Sources: USPTO Patent Grant XML, Patent Center, EPO & CIPO • Normalized by IDiyas Innovation Graph. Methodology & provenance architecturePlease report any incorrect information to [email protected]

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