The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 29, 2019

Filed:

Mar. 13, 2013
Applicant:

454 Life Sciences Corporation, Branford, CT (US);

Inventors:

Yi-Ju Chen, New Haven, CT (US);

Chiu Tai Andrew Wong, Northford, CT (US);

Assignee:

454 Life Sciences Corporation, Branford, CT (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); G06F 19/12 (2011.01); G06F 19/20 (2011.01); G06F 19/22 (2011.01); G06F 19/24 (2011.01);
U.S. Cl.
CPC ...
G06F 19/12 (2013.01); G06F 19/20 (2013.01); G06F 19/22 (2013.01); G06F 19/24 (2013.01);
Abstract

An embodiment of a method for generating a flow order that minimizes the accumulation of phasic synchrony error in sequence data is described that comprises the steps of: (a) generating a plurality of sequential orderings of nucleotides species comprising a k-base length, wherein the sequential orderings define a sequence of introduction of nucleotide species into a sequencing by synthesis reaction environment; (b) simulating acquisition of sequence data from one or more reference genomes using the sequential orderings, wherein the sequence data comprises an accumulation of phasic synchrony error; and (c) selecting one or more of the sequential orderings using a read length parameter and an extension rate parameter.


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