The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 23, 2004
Filed:
Mar. 10, 1999
Applicant:
Inventors:
Peter E. Nielsen, 2980 Kokkedal, DK;
Michael Egholm, Wayland, MA (US);
Rolf H. Berg, 2960 Rungsted Kyst, DK;
Ole Buchardt, late of Værlose, DK;
Assignee:
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/800 ; C12Q 1/68 ; G01N 3/3566 ;
U.S. Cl.
CPC ...
A61K 3/800 ; C12Q 1/68 ; G01N 3/3566 ;
Abstract
A novel class of compounds known as peptide nucleic acids, bind complementary DNA and RNA strands, and generally do so more strongly than the corresponding DNA or RNA strands while exhibiting increased sequence specificity and solubility. The peptide nucleic acids comprise ligands selected from a group consisting of naturally-occurring nucleobases and non-naturally-occurring nucleobases, including 2,6-diaminopurine, attached to a polyamide backbone, and contain alkyl amine side chains.