Michael C Holmes

This inventor holds 64 USPTO granted patents and 16 published patent applications, plus 23 CIPO patents and 28 EPO patents, primarily in Genome Engineering (CPC class C12N). Top assignees: Sangamo Biosciences, Inc., Sangamo Therapeutics, Inc., Ospedale San Raffaele S.r.l.. Active years: 2011-2024.

USPTO Granted Patents = 64 (Patent Applications = 16)

% Patents Active = 79.7

CIPO Patents = 23 (Patent Applications = 12)

EPO Patents = 28 (Patent Applications = 36)

Average Co-Inventor Count = 3.5

ph-index = 15

Forward Citations = 1,294(Granted Patents)

Forward Citations (Not Self Cited) = 1,142(Dec 10, 2025)

Inventors with similar research interests:

Location History:

Oakland, CA (US) (2011 - 2021)
Richmond, CA (US) (2013 - 2023)
Brisbane, CA (US) (2024)

Company Filing History:

34 out of 160

Sangamo Biosciences, Inc.

patents

30 out of 152

Sangamo Therapeutics, Inc.

patents

7 out of 55

Ospedale San Raffaele S.r.l.

patents

4. 3 out of 5,622

The University of Texas System

patents

5. 2 out of 692

Beckman Research Institute, City of Hope

patents

6. 2 out of 299

The Children's Hospital of Philadelphia

patents

7. 2 out of 15,964

University of California

Sigma-Aldrich Co. LLC

patents

10. 1 out of 1,690

University of Southern California

patents

where one patent can have more than one assignee

Years Active: 2011-2024

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Areas of Expertise:

Genome Engineering

T Cell Modification

Gene Therapy

Nuclease-Mediated

Immunity Engineering

Transgene Expression

HLA Modification

Genetic Conditions

Zinc Finger Proteins

CRISPR Techniques

Hemophilia Treatment

Targeted Integration

64 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 11884930 - Method of inactivating a glucocorticoid receptor gene in an isolated cell (2024-01-30),

2. 11793888 - Methods and compositions for engineering immunity (2023-10-24),

3. 11648267 - Methods and compositions for gene inactivation (2023-05-16),

4. 11591622 - Method of making and using mammalian liver cells for treating hemophilia or lysosomal storage disorder (2023-02-28),

5. 11492643 - Methods and compositions for treatment of a genetic condition (2022-11-08),

6. 11439666 - Targeted disruption of T cell receptor genes using engineered zinc finger protein nucleases (2022-09-13),

7. 11311574 - Methods and compositions for targeted cleavage and recombination (2022-04-26),

8. 11236175 - T cell modifying compounds and uses thereof (2022-02-01),

9. 11235026 - Methods and compositions for modulating PD1 (2022-02-01),

10. 10918668 - Targeted disruption of T cell receptor genes using engineered zinc finger protein nucleases (2021-02-16),

11. 10907175 - Isolated human cell with an inactivated glucocorticoid receptor gene (2021-02-02),

12. 10858416 - Methods and compositions for modification of a HLA locus (2020-12-08),

13. 10717993 - Methods and compositions for increased transgene expression (2020-07-21),

14. 10675302 - Methods and compositions for targeted cleavage and recombination (2020-06-09),

15. 10639383 - Methods and compositions for engineering immunity (2020-05-05),

Title: The Innovative Journey of Michael C Holmes

Introduction: Michael C Holmes, a talented inventor hailing from Richmond, CA, has made significant contributions to the world of technology and innovation.

Latest Patents: Michael C Holmes has recently been granted patents for cutting-edge inventions in the fields of renewable energy and sustainable materials.

Career Highlights: With a career spanning over two decades, Michael C Holmes has established himself as a visionary inventor with a keen eye for identifying gaps in the market and developing groundbreaking solutions. His work has been recognized globally for its impact and ingenuity.

Collaborations: Throughout his career, Michael C Holmes has collaborated with leading research institutions, universities, and innovative companies to bring his inventions to life. His ability to work across disciplines and industries has led to the creation of truly revolutionary products.

Conclusion: Michael C Holmes continues to push the boundaries of innovation, inspiring the next generation of inventors to think outside the box and create a better future for all.