The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 16, 2021
Filed:
Mar. 26, 2018
Applicants:
Sangamo Therapeutics, Inc., Richmond, CA (US);
Ospedale San Raffaele Srl, Milan, IT;
Inventors:
Philip D. Gregory, Richmond, CA (US);
Michael C. Holmes, Richmond, CA (US);
David Paschon, Richmond, CA (US);
Lei Zhang, Richmond, CA (US);
Maria Chiara Bonini, Milan, IT;
Pietro Genovese, Milan, IT;
Zulma Magnani, Milan, IT;
Sara Mastaglio, Milan, IT;
Luigi Naldini, Milan, IT;
Assignees:
Sangamo Therapeutics, Inc., Richmond, CA (US);
Ospedale San Raffaele SRL, Milan, IT;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/26 (2015.01); C12N 15/87 (2006.01); A61K 39/00 (2006.01); C12N 15/86 (2006.01); C12N 15/90 (2006.01);
U.S. Cl.
CPC ...
A61K 35/26 (2013.01); A61K 39/0011 (2013.01); A61K 39/001188 (2018.08); C12N 15/86 (2013.01); C12N 15/87 (2013.01); C12N 15/907 (2013.01); A61K 2039/5156 (2013.01); A61K 2039/5158 (2013.01); C12N 2501/515 (2013.01); C12N 2510/00 (2013.01); C12N 2740/16043 (2013.01);
Abstract
Disclosed herein are methods and compositions for modifying TCR genes, using nucleases (zinc finger nucleases or TAL nucleases) to modify TCR genes.