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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11884930 B1

PDFFull Text
Date of Patent:
Jan. 30, 2024

Filed:

Dec. 18, 2020

Method of inactivating a glucocorticoid receptor gene in an isolated cell

Applicants:

Sangamo Therapeutics, Inc., Brisbane, CA (US);

City of Hope, Duarte, CA (US);

Inventors:

Andreas Reik, Brisbane, CA (US);

Michael Jensen, Sierra Madre, CA (US);

Michael C. Holmes, Brisbane, CA (US);

Philip D. Gregory, Brisbane, CA (US);

Dale Ando, Brisbane, CA (US);

Assignees:

Sangamo Biosciences, Inc., Brisbane, CA (US);

City of Hope, California, CA;

Attorney:

Foley & Lardner LLP

Primary Examiner:

Michael C Wilson

Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12N 15/86 (2006.01); C12N 15/62 (2006.01); C07K 14/72 (2006.01); C12N 9/22 (2006.01); G01N 33/74 (2006.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); C07K 14/721 (2013.01); C12N 9/22 (2013.01); C12N 15/62 (2013.01); G01N 33/743 (2013.01); C12N 2710/10043 (2013.01); C12N 2740/15043 (2013.01); G01N 2333/723 (2013.01);
Abstract

Disclosed herein are methods and compositions for inactivation of the human glucocorticoid receptor (GR) gene by targeted cleavage of genomic DNA encoding the GR. Such methods and compositions are useful, for example, in therapeutic applications which require retention of immune function during glucocorticoid treatment.

Find Patent Forward Citations

Reik, Andreas. (2024). Method of inactivating a glucocorticoid receptor gene in an isolated cell (U.S. Patent No. 11884930). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11884930

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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