Location History:
- Los Angeles, CA (US) (2020 - 2023)
- Pasadena, CA (US) (2022 - 2024)
Company Filing History:
Years Active: 2020-2025
Title: Michael B Elowitz: Innovator in Synthetic Biology
Introduction
Michael B Elowitz is a prominent inventor based in Pasadena, CA, known for his significant contributions to the field of synthetic biology. With a total of 14 patents to his name, Elowitz has made remarkable advancements in the understanding and manipulation of biological systems.
Latest Patents
Among his latest patents is a synthetic system for tunable thresholding of protein signals. This invention includes methods, compositions, and kits that are suitable for thresholding protein signals. The synthetic protein circuits developed in this patent respond to inputs only when they exceed or fall below a certain threshold concentration. Additionally, the threshold value can be adjusted, providing flexibility in applications. This invention also includes methods for treating diseases characterized by aberrant signaling.
Another notable patent is for a method for robust control of gene expression. This patent outlines methods, compositions, and kits that enable robust and tunable control of gene expression. It features rationally designed circuits, including miRNA-level and protein-level incoherent feed-forward loop circuits, which maintain the expression of a payload at an effective level. The circuit comprises a promoter linked to a polynucleotide encoding a fusion protein that includes a payload protein, a protease, and self-cleaving peptide sequences.
Career Highlights
Michael B Elowitz is affiliated with the California Institute of Technology, where he continues to push the boundaries of synthetic biology. His work has garnered attention for its innovative approach to biological engineering and its potential applications in medicine and biotechnology.
Collaborations
Elowitz has collaborated with notable colleagues, including Lucy S Chong and Mark William Budde, contributing to a dynamic research environment that fosters innovation and discovery.
Conclusion
Michael B Elowitz stands out as a leading inventor in synthetic biology, with a focus on developing innovative methods for controlling biological systems. His contributions have the potential to revolutionize the field and improve therapeutic strategies for various diseases.
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