The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 14, 2023
Filed:
Dec. 02, 2019
Applicant:
California Institute of Technology, Pasadena, CA (US);
Inventors:
Yaron E. Antebi, Pasadena, CA (US);
James Linton, Pasadena, CA (US);
Michael Elowitz, Los Angeles, CA (US);
Heidi Klumpe, Pasadena, CA (US);
Assignee:
California Institute of Technology, Pasadena, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); G01N 33/569 (2006.01); G01N 33/566 (2006.01); G01N 33/50 (2006.01); G06F 17/18 (2006.01); C07K 14/71 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6872 (2013.01); C07K 14/71 (2013.01); G01N 33/5041 (2013.01); G01N 33/566 (2013.01); G01N 33/56966 (2013.01); G06F 17/18 (2013.01); A01K 2227/105 (2013.01); G01N 2333/51 (2013.01); G01N 2333/71 (2013.01); G01N 2500/02 (2013.01); G01N 2500/10 (2013.01);
Abstract
Methods and compositions are provided for the selective activation of a BMP-dependent response in certain cell types. Methods include identifying a ligand or ligand combinations as well as cell receptor profiles that result in selectively activating a ligand-dependent response through interactions with ligand receptors on a first cell type that do not activate the ligand-dependent response in a second cell type.