Merry R Sherman is a prominent inventor based in San Carlos, CA (US). She has made significant contributions to the field of bioconjugate chemistry, holding a total of 12 patents. Her work focuses on the development of innovative therapeutic agents that enhance biological potency and reduce immunogenicity.

Latest Patents

Among her latest patents is the invention of PEG-urate oxidase conjugates and their applications. This invention involves a naturally occurring or recombinant urate oxidase covalently coupled to poly(ethylene glycol) (PEG). The resulting PEG-uricase conjugates are designed to be substantially non-immunogenic while retaining at least 75% of the uricolytic activity of the unmodified enzyme. Another notable patent involves polymer conjugates of interferon-beta with enhanced biological potency. This invention provides methods for synthesizing polymer conjugates of cytokines, particularly non-glycosylated interferon-beta, which retain high biological potency and exhibit an extended half-life in vivo.

Career Highlights

Merry R Sherman has worked with several reputable organizations, including Mountain View Pharmaceuticals, Inc. and Duke University. Her experience in these institutions has allowed her to advance her research and contribute to the development of innovative therapeutic solutions.

Collaborations

Throughout her career, she has collaborated with notable colleagues such as L David Williams and Mark G P Saifer. These collaborations have further enriched her research and innovation in the field.

Conclusion

Merry R Sherman is a distinguished inventor whose work in bioconjugate chemistry has led to significant advancements in therapeutic applications. Her innovative patents and collaborations highlight her commitment to enhancing medical treatments and improving patient outcomes.

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