The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 06, 2012
Filed:
Sep. 25, 2003
Alexa L Martinez, San Jose, CA (US);
Merry R Sherman, San Carlos, CA (US);
Mark G. P. Saifer, San Carlos, CA (US);
L. David Williams, Fremont, CA (US);
Alexa L Martinez, San Jose, CA (US);
Merry R Sherman, San Carlos, CA (US);
Mark G. P. Saifer, San Carlos, CA (US);
L. David Williams, Fremont, CA (US);
Mountain View Pharmaceuticals, Inc., Menlo Park, CA (US);
Abstract
Methods are provided for the preparation of conjugates of a variety of bioactive components, especially proteins, with water-soluble polymers (e.g., poly(ethylene glycol) and derivatives thereof), which conjugates have reduced antigenicity and immunogenicity compared to similar conjugates prepared using poly(ethylene glycol) containing a methoxyl or another alkoxyl group. The invention also provides conjugates prepared by such methods, compositions comprising such conjugates, kits containing such conjugates or compositions and methods of use of the conjugates and compositions in diagnostic and therapeutic protocols.